Statin Therapy and Vasospastic Angina

نویسندگان

چکیده

Statin treatment improves endothelial dysfunction and decreases plaque volume in patients with obstructive coronary artery disease (OCAD) as a pleiotropic mechanism. Clinical outcomes OCAD under statin therapy are favorable compared those for without statins. However, the effect of statins may be uncertain vasospastic angina nonobstructive (VSA-NOCAD). Several researchers South Korea Japan have reported on effectiveness VSA-NOCAD. Flow-mediated dilatation was shown to improved VSA not effective reducing major cardiovascular events (MACEs) VSA-NOCAD, although after propensity score matching, prognosis better Furthermore, high-intensity showed no clinical utility mitigating MACEs

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ژورنال

عنوان ژورنال: Journal of coronary artery disease

سال: 2023

ISSN: ['2434-2173']

DOI: https://doi.org/10.7793/jcad.29.23-00006